Upregulation of basophil surface markers CD63 and CD203c uponexposure to allergens was first shown almost two decades ago(Sainte-Laudy et al., 1998). The strong correlation between theseinducible biomarkers and outcomes of food allergen challenge isproving to be a valuable clinical tool (Czechowska et al., 2019; Koplinet al., 2019; Santos et al., 2014).